Meridor is heading the Israeli delegation to the conference, after Prime Minister Benjamin Netanyahu cancelled his planned trip to Washington.
"I regret to disappoint those who expected clashes against Israel in the summit," he said. "The atmosphere here is good, both in the speeches and in talks on the margins of the conference."
The minister also declared that Israel maintains two nuclear reactors at this time and ensures their safe operation.
"Israel has two nuclear reactors that contain hazardous materials," he said. "We have been operating them in an orderly manner for years now to ensure protection against nuclear dangers."
The major threat: Iran
In its concluding statement, as expected, Israel focused on the Iranian nuclear threat, without explicitly referring to Tehran:
"The greatest threat to peace is that the world's most dangerous regimes and the world's most dangerous terror groups would acquire the world's most dangerous weapons," Israel's statement read. "Over the last three decades, we have seen an alarming increase in the risk of this threat materializing, especially in the Middle East."
"This threat has been magnified by the possibility that terror supporting states developing nuclear weapons might give these weapons and other nuclear materials to their non-state proxies in the hope of avoiding culpability for their actions.
"Israel acutely understands this threat because a regime that illicitly seeks nuclear weapons and openly calls for Israel's destruction is supporting terror proxies that continuously attack Israel's civilians with missiles, rockets and other means."
Roni Sofer contributed to the story