One of the main western-backed rebel groups announced on Sunday that it had dissolved itself and joined a larger Islamist alliance, weeks into a battle which saw it lose ground and men to more powerful al Qaeda insurgents.
Hazzm is one of the last remnants of non-jihadist opposition to President Bashar Assad in northern Syria, much of which has been seized by the Nusra Front and Islamic State, an offshoot of al-Qaeda that controls roughly a third of Syria.
The statement posted online said its fighters would join the Shamiyah Front, an alliance of Islamist brigades in Aleppo, to prevent further bloodshed.
The decision comes after heavy weekend fighting between it and the Nusra Front, al Qaeda's official Syria wing. Both Hazzm, which is part of the Free Syria Army collection of mainstream rebel groups, and Nusra fight the government.
On Saturday, the Nusra Front drove Hazzm out of a strategic northern Regiment 46 base in Aleppo province and killed around 30 of its fighters, said the Syrian Observatory for Human Rights, which tracks the conflict.
The weakness of the mainstream Syrian opposition has complicated diplomatic efforts to end the conflict that has killed around 200,000 people.
United Nations peace mediator Staffan de Mistura met with Syrian officials on Saturday and Sunday to discuss a freeze in the fighting in Aleppo.
De Mistura has said Syria has expressed a willingness to halt all aerial and artillery bombing in the city for six weeks.
He said Damascus would announce the start date of the local ceasefire. His office said on Sunday a mission had been sent to Aleppo to ensure humanitarian aid could increase significantly once the freeze was announced, and to monitor any violation of the freeze.