The wounded woman's husband managed to escape the vehicle unharmed. A passerby, around 20 years old, who tried to put out the fire that broke out was lightly hurt from smoke inhalation.
Another man was lightly hurt when the car rolled back and hit another vehicle - which was partially damaged. The vehicle that was hit by the Molotov cocktail was completely burned.
The woman, who is suffering from first- and second-degree burns on 15 percent of her body, was taken to Hadassah Medical Center in Jerusalem's Ein Karem, while the man was taken to Shaare Zedek Medical Center in the capital.
The attack happened at the Beit Hanina Junction, on the way from the Benzion Netanyahu interchange to Pisgat Ze'ev.
Police and Border Police forces were dispatched to the area and are searching for suspects.