Investigators raided the Ministry in search of evidence regarding donations received while Olemrt served as Industry, Trade and Labor minister. They were also looking for documents that could indicate whether Morris (Moshe) Talansky, the businessman involved in the affair, turned to Olmert in a bid to promote his company.
Meanwhile, police also questioned billionaire businessmen Sheldon Adelson and Daniel Abrams in connection with the investigation.
The latest raid marks the second one in two days. On Monday, police investigators raided city hall. Police confiscated various documents reportedly related to the corruption allegations against PM Olmert.
Five months earlier police raided several government offices, including those of the Jerusalem Municipality, as part of a different investigation against Olmert.
According to reports earlier Tuesday, as part of the probe investigators are looking into the possibility that at some point during his tenure as mayor of Jerusalem between 1993 and 2003 Olmert ordered the installation of speed bumps near the home of Talansky's son, Yitzhak, in the Har-Nof neighborhood in the capital.
The order was given, police suspect, after the businessman complained that speeding drivers were endangering his son's family.