But Recep Tayyip Erdogan says that while Syria wants Turkey's mediation, Israeli leaders believe the Turkish premier is biased against Israel and cannot be a fair mediator.
Erdogan was speaking late Tuesday before departing for a visit to Damascus.
Turkey mediated several rounds of indirect talks last year before they came to a halt following Israel's Gaza offensive. Ties between Israel and Turkey have deteriorated since then with Erdogan harshly criticizing Israeli policies.
French President Nicolas Sarkozy has also said his country was ready to facilitate a resumption of Syrian-Israeli talks.