The Health Ministry reported Monday evening that 169 Israelis have tested positive for the novel coronavirus in the last 24 hours, 125 of them since midnight, in what constitutes Israel's largest leap in daily cases since the end of April.
The fresh spike in positive diagnoses raises the number of active coronavirus patients to 2,607 as only 13 patients recover during the same time period.
There are currently 29 patients in serious condition and 23 of them are receiving respiratory assistance.
Since the onset of the pandemic in the country, 18,032 Israelis have contracted the virus and 298 patients succumbed to complications of COVID-19, the disease caused by coronavirus.
The ministry also reported that 8,891 coronavirus tests have been conducted since midnight, a relatively low figure when compared to previous days.
Tel Aviv has emerged as Israel's potential coronavirus hotspot after reporting a major rise in new diagnoses over the past three days.
The Health Ministry said 46 new COVID-19 cases were recorded in the central city over the past 72 hours, representing a 7% increase.
The figure is unusual for the city, which has seen a consistent decline in the number of new diagnoses throughout the health crisis.
Health officials said the increase is partly due to the outbreak in Yaffa, which is part of Tel Aviv's municipality, where several schools have already been closed after a number of students and staff members were confirmed to have been infected.