Syrian air defenses intercepted Israeli missiles over the capital Damascus, state media said early on Thursday without specifying the nature of the targets.
Syrian state-run Ikhbariyah TV said the attack was launched from over the Golan Heights as well as through Lebanese airspace.
State news agency SANA said air defenses downed most of the missiles before they reached their targets. There were no immediate reports of damage or casualties.
British-based war monitor the Syrian Observatory for Human Rights said several missiles were fired on Syrian government forces and Iranian militias near Damascus, including in al-Kiswa town and Mezze military airport.