חיסון הצוות הרפואי
A member of the medical staff receiving the coronavirus vaccine at Sheba Medical Center near Tel Aviv
Photo: Yariv Katz
A member of the medical staff receiving the coronavirus vaccine at Sheba Medical Center near Tel Aviv

Israel study: One vaccine shot sees strong response in COVID recoveries

Researchers find that among 17 medical staff who had previously contracted the virus, a single dose of Pfizer inoculation increased antibody levels to levels found in those who had not contracted the disease but received both doses

TPS |
Published: 02.14.21 , 16:30
Researchers from Bar-Ilan University and Ziv Medical Center have presented preliminary evidence that people previously infected with coronavirus responded positively and strongly to one dose of the Pfizer vaccine, regardless of when they were infected and whether or not they had detectable antibodies prior to being inoculated.
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  • The study was conducted on a group of 514 staff members at Ziv Medical Center in Safed, 17 of whom were infected with COVID-19 between one and 10 months before receiving the first dose of the vaccine.
    2 צפייה בגלריה
    חיסון הצוות הרפואי
    חיסון הצוות הרפואי
    A member of the medical staff receiving the coronavirus vaccine at Sheba Medical Center near Tel Aviv
    (Photo: Yariv Katz)
    Antibody levels of the group were measured before and after receiving the shot in order to determine the response to the vaccine.
    The response among those previously infected was so effective that it opens the debate as to whether one dose of the vaccine may suffice in certain situations.
    “This finding can help countries make informed decisions regarding vaccine policy – for instance, whether those previously infected should be vaccinated in priority and, if so, with how many doses,” says Prof. Michael Edelstein of Bar-Ilan University's Faculty of Medicine, who led the study.
    “It also offers reassurance that not having detectable antibodies after being infected does not necessarily mean that post-infection protection is lost,” he says.
    2 צפייה בגלריה
    מחלקת קורונה בבית חולים בצפת
    מחלקת קורונה בבית חולים בצפת
    A coronavirus ward at Ziv Medical Center in Safed
    (Photo: AP)
    However, the researchers emphasized that their findings should be confirmed in a larger cohort before reaching definitive conclusions.
    The researchers are continuing to track healthcare workers after their second dose to better understand how long the vaccine will protect against COVID-19 in different groups of people.
    France on Friday recommended that people who have already recovered from Covid-19 receive a single vaccine dose, becoming the first country to issue such guidance. 
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